Fayu Yang is currently an Associate Professor at the College of Veterinary Medicine, Lanzhou University (since 2025). His research focuses on virus–host interactions, antiviral drug discovery, and the development and optimization of gene editing tools.
RESEARCH EXPERIENCE
Jul 2025 – Present
Associate Professor, College of Veterinary Medicine, Lanzhou University
Sep 2022 – Jun 2025
Postdoctoral Fellow, College of Veterinary Medicine, Lanzhou University
EDUCATION
Sep 2019 – Jun 2022
Ph.D. in Veterinary Pharmacology, Chinese Academy of Agricultural Sciences, Supervisor: Professor Feng Gu
Sep 2013 – Jul 2016
M.S. in Biology, Wenzhou Medical University, Supervisor: Professor Jia Qu/ Feng Gu
Sep 2009 – Jul 2013
B.S. in Biotechnology, Inner Mongolia University of Science and Technology
RESEARCH GRANTS
6. Talent Scientific Fund of Lanzhou University. Jul 2025 – Jun 2030
5. National Natural Science Foundation of China (32503014). Jan 2026 – Dec 2028
4. State Key Laboratory for Animal Disease Control and Prevention (SKLADCP2025LZU-02). Sep 2025 – Sep 2027
3. Fundamental Research Funds for the Central Universities (lzujbky-2024-pd08). Jul 2024 – Jun 2026
2. China Postdoctoral Science Foundation (2023M731465). Jun 2023 – Feb 2025
1. Natural Science Foundation of Gansu province (23JRRA1134). Jul 2023 – Jun 2024
11. Wenchao Xue#, Fayu Yang#, Zhonghui Zhang, Xiangle Zhang, Yuxi Yang, Yuxuan Li, Zhengshan Feng, Yong Li, Xi Lan, Haixue Zheng, Zixiang Zhu*, Shilei Zhang*. Heparan sulfate as an attachment factor for ASFV is restricted by host HB-EGF. Cell Molecular Life Sciences. 2026, 83(1):186.
10. Fayu Yang, Saba Aliyari, Zixiang Zhu, Haixue Zheng, Genhong Cheng*, Shilei Zhang*. CRISPR-Cas: A Game-Changer in the Fight Against Viral Infections and Vaccine Development. Trends in Microbiology. 2025, 33(6):650-664.
9. Fayu Yang, Nan Wei, Shuo Cai, Jing Liu, Qingping Lan, Hao Zhang, Lu Shang, Bo Zheng, Mi Wang, Yingchun Liu, Lifang Zhang, Chenzhong Fei, Wu Tong, Changlong Liu, Ersheng Kuang, Guangzhi Tong*, Feng Gu*. Genome-wide CRISPR screens identify CLC-2 as a drug target for anti-herpesvirus therapy: tackling herpesvirus drug resistance. Science China Life Science. 2025, 68(2):515-526.
8. Fayu Yang, Yuxi Yang, Xiaoyun Li, Saba Aliyari, Guoliang Zhu, Zixiang Zhu*, Haixue Zheng*, Shilei Zhang*. A Nanobody-based TRIM-away targets the intracellular protein degradation of African Swine Fever Virus. Virology. 2024, 600:110283.
7. Nan Wei, Lu Shang, Jing Liu, Mi Wang, Yingchun Liu, Chuangang Zhu, Chenzhong Fei, Lifang Zhang, Fayu Yang*, Feng Gu*. Engineered Staphylococcus auricularis Cas9 with high-fidelity. FASEB Journal. 2023, 37(8):e23060. (Co‑corresponding author)
6. Fayu Yang, Hao Zhang, Shuo Cai, Kiran Imtiaz, Mingchun Li, Mi Wang, Yingchun Liu, Feiqun Xue, Lifang Zhang*, Feng Gu*. Green Fluorescent Protein Tagged Polycistronic Reporter System Reveals Functional Editing Characteristics of CRISPR-Cas. CRISPR Journal. 2022, 5(2):254-263.
5. Fayu Yang, Nan Wei, Zhihao Zhang, Mi Wang, Yingchun Liu, Lifang Zhang, Feng Gu*. Genome Editing of Corynebacterium glutamicum Mediated with Cpf1 Plus Ku/LigD. Biotechnology Letters. 2021, 43(12):2273-2281.
4. Fayu Yang, Xianglian Ge, Xiubin He, Xiexie Liu, Chenchen Zhou, Huihui Sun, Junsong Zhang, Junzhao Zhao, Zongming Song, Jia Qu, Changbao Liu, Feng Gu*. Functional Non-homologous End Joining Pattern Triggered by CRISPR/Cas9 in Human Cells. Journal of Genetics and Genomics. 2018, 45(6):329-332.
3. Fayu Yang, Changbao Liu, Ding Chen, Mengjun Tu, Haihua Xie, Huihui Sun, Xianglian Ge, Lianchao Tang, Jin Li, Jiayong Zheng, Zongming Song, Jia Qu, Feng Gu*. CRISPR/Cas9-loxP-Mediated Gene Editing as a Novel Site-Specific Genetic Manipulation Tool. Molecular Therapy-Nucleic Acids. 2017, 7: 378–386.
2. Fengtao Dang#, Fayu Yang#, Yeqin Yang, Xianglian Ge, Ding Chen, Liu Zhang, Xinping Yu, Feng Gu*, Yihua Zhu*. A Novel Mutation, p.F32I, in GJA8 (Cx50) Causes Human Dominant Congenital Cataracts. International Journal of Ophthalmology. 2016, 9(11):1561-1567.
1. Fayu Yang, et al. Local Polyploidy Phenomenon in Escherichia coli and its Significance in Genetic Engineering. BioRxiv. 2018. doi: https://doi.org/10.1101/335448.
